Publications
2024
IMD-mediated innate immune priming increases Drosophila survival and reduces pathogen transmission.
Prakash A, Fenner F, Shit B, Salminen TS, Monteith KM, Khan I, Vale PF
PLOS Pathogens. 2024; 10.1371/journal.ppat.1012308
Negative immune regulation contributes to disease tolerance in Drosophila melanogaster.
Prakash A, Monteith KM, Vale PF.
Physiological Entomology. Accepted.
https://doi.org/10.1111/phen.12464
Mitochondrial perturbation in immune cells enhances cell-mediated innate immunity in Drosophila.
Vesala L, Basikhina Y, Tuomela T, Nurminen A, Siukola E, Vale PF, Salminen TS.
BMC Biology. 2024;22: 60. doi:10.1186/s12915-024-01858-5
Salminen TS, Vesala L, Basikhina Y, Kutzer M, Tuomela T, Lucas R, Monteith KM, Prakash A, Tietz, T, and Vale PF.
bioRxiv; 2024. p. 2024.03.28.587162. doi:10.1101/2024.03.28.587162
Monteith K, Thornhill P, Vale PF.
bioRxiv; 2024. p. 2024.05.09.593162. doi:10.1101/2024.05.09.593162
Mitochondrial background can explain variable costs of immune deployment.
Kutzer MAM, Cornish B, Jamieson M, Zawistowska O, Monteith KM, Vale PF.
Journal of Evolutionary Biology, 37(4), 442-450.
2023
Duox and Jak/Stat signalling influence disease tolerance in Drosophila during Pseudomonas entomophila infection.
Prakash A, Monteith KM, Bonnet M, Vale PF.
Developmental & Comparative Immunology. 2023; 104756. doi:10.1016/j.dci.2023.104756
Kutzer MAM, Gupta V, Neophytou K, Doublet V, Monteith KM, Vale PF.
Open Biology. 2023;13: 230025. doi:10.1098/rsob.230025
2022
Ageing leads to reduced specificity of antimicrobial peptide responses in Drosophila melanogaster.
Shit B, Prakash A, Sarkar S, Vale PF, Khan I.
Proceedings of the Royal Society B: Biological Sciences. 2022;289: 20221642. doi:10.1098/rspb.2022.1642
Savola E, Vale P, Walling C.
Journal of Insect Physiology. 2022; 104428. doi:10.1016/j.jinsphys.2022.104428
Romano V, Lussiana A, Monteith KM, MacIntosh AJJ, Vale PF.
Biology Letters. 2022;18: 20220233. doi:10.1098/rsbl.2022.0233
Mechanisms of damage prevention, signalling and repair impact disease tolerance.
Prakash A, Monteith KM, Vale PF.
Proceedings of the Royal Society B: Biological Sciences. 2022;289: 20220837. doi:10.1098/rspb.2022.0837
Variation in mitochondrial DNA affects locomotor activity and sleep in Drosophila melanogaster.
Anderson L, Camus MF, Monteith KM, Salminen TS, Vale PF.
Heredity. 2022; 1–8. doi:10.1038/s41437-022-00554-w
2021
Dissecting genetic and sex-specific sources of host heterogeneity in pathogen shedding and spread.
Siva-Jothy JA, Vale PF.
PLOS Pathogens. 2021;17: e1009196. doi:10.1371/journal.ppat.1009196
Testing evolutionary explanations for the lifespan benefit of dietary restriction in fruit flies (Drosophila melanogaster). Savola E, Montgomery C, Waldron FM, Monteith KM, Vale P, Walling C.
Evolution. 2021;75: 450–463. doi:10.1111/evo.14146
Carry on caring: infected females maintain their parental care despite high mortality.
Ratz T, Monteith KM, Vale PF, Smiseth PT.
Behavioral Ecology. 2021 [cited 21 Apr 2021]. doi:10.1093/beheco/arab028
Epidemiological dynamics of viral infection in a marine picoeukaryote.
Listmann L, Heath S, Vale PF, Schaum CE, Collins S.
bioRxiv; 2021. p. 2021.03.23.436719. doi:10.1101/2021.03.23.436719
2020
White LA, Siva-Jothy JA, Craft ME, Vale PF.
Proceedings of the Royal Society B: Biological Sciences. 2020;287: 20201653. doi:10.1098/rspb.2020.1653
Drosophila as a Model System to Investigate the Effects of Mitochondrial Variation on Innate Immunity.
Salminen TS, Vale PF.
Frontiers in Immunology. 2020;11. doi:10.3389/fimmu.2020.00521
How are arbovirus vectors able to tolerate infection?
Oliveira JH, Bahia AC, Vale PF.
Developmental & Comparative Immunology. 2020;103: 103514. doi:10.1016/j.dci.2019.103514
Terminal investment strategies following infection are dependent on diet.
Hudson AL, Moatt JP, Vale PF.
Journal of Evolutionary Biology. 2020;33: 309–317. doi:10.1111/jeb.13566
2019
Population-Level Disease Dynamics Reflect Individual Heterogeneities in Transmission.
Siva-Jothy JA, White LA, Craft ME, Vale PF.
bioRxiv; 2019. p. 735480. doi:10.1101/735480
Viral infection causes sex-specific changes in fruit fly social aggregation behaviour.
Siva-Jothy JA, Vale PF.
Biology Letters. 2019;15: 20190344. doi:10.1098/rsbl.2019.0344
2018
The influence of parasites on insect behavior.
Vale PF, Siva-Jothy JA, Morrill A, Forbes MR.
in Insect Behavior: from mechanisms to ecological and evolutionary consequences. 2018;1.
Disease Tolerance: Linking Sickness Behaviours to Metabolism Helps Mitigate Malaria.
Vale PF.
Curr Biol. 2018;28: R606–R607. doi:10.1016/j.cub.2018.04.031
Oral Bacterial Infection and Shedding in Drosophila melanogaster.
Siva-Jothy JA, Prakash A, Vasanthakrishnan RB, Monteith KM, Vale PF.
J Vis Exp. 2018. doi:10.3791/57676
Navigating infection risk during oviposition and cannibalistic foraging in a holometabolous insect.
Siva-Jothy JA, Monteith KM, Vale PF.
Behav Ecol. 2018;29: 1426–1435. doi:10.1093/beheco/ary106
2017
Infection avoidance behavior: Viral exposure reduces the motivation to forage in female Drosophila melanogaster.
Vale PF, Jardine MD.
Fly (Austin). 2017;11: 3–9. doi:10.1080/19336934.2016.1207029
Virus Resistance Is Not Costly in a Marine Alga Evolving under Multiple Environmental Stressors.
Heath SE, Knox K, Vale PF, Collins S.
Viruses. 2017;9. doi:10.3390/v9030039
The route of infection determines Wolbachia antibacterial protection in Drosophila.
Gupta V, Vasanthakrishnan RB, Siva-Jothy J, Monteith KM, Brown SP, Vale PF.
Proc Biol Sci. 2017;284. doi:10.1098/rspb.2017.0809
Nonlinear disease tolerance curves reveal distinct components of host responses to viral infection.
Gupta V, Vale PF.
R Soc Open Sci. 2017;4: 170342. doi:10.1098/rsos.170342
Costs and benefits of sublethal Drosophila C virus infection.
Gupta V, Stewart CO, Rund SSC, Monteith K, Vale PF.
J Evol Biol. 2017;30: 1325–1335. doi:10.1111/jeb.13096
2016
Beyond killing: Can we find new ways to manage infection?
Vale PF, McNally L, Doeschl-Wilson A, King KC, Popat R, Domingo-Sananes MR, et al.
Evol Med Public Health. 2016;2016: 148–157. doi:10.1093/emph/eow012
2015
Costs of CRISPR-Cas-mediated resistance in Streptococcus thermophilus.
Vale PF, Lafforgue G, Gatchitch F, Gardan R, Moineau S, Gandon S.
Proc Biol Sci. 2015;282: 20151270. doi:10.1098/rspb.2015.1270
Sex-specific behavioural symptoms of viral gut infection and Wolbachia in Drosophila melanogaster.
Vale PF, Jardine MD.
J Insect Physiol. 2015;82: 28–32. doi:10.1016/j.jinsphys.2015.08.005
Host Genotype and Coinfection Modify the Relationship of within and between Host Transmission.
Susi H, Vale PF, Laine A-L.
Am Nat. 2015;186: 252–263. doi:10.1086/682069
Co-infection alters population dynamics of infectious disease.
Susi H, Barrès B, Vale PF, Laine A-L.
Nat Commun. 2015;6: 5975. doi:10.1038/ncomms6975
Microbiome engineering could select for more virulent pathogens.
McNally L, Vale PF, Brown SP.
bioRxiv; 2015. p. 027854. doi:10.1101/027854
2014
Limiting damage during infection: lessons from infection tolerance for novel therapeutics.
Vale PF, Fenton A, Brown SP.
PLoS Biol. 2014;12: e1001769. doi:10.1371/journal.pbio.1001769
The evolution of resistance against good and bad infections.
Gandon S, Vale PF.
J Evol Biol. 2014;27: 303–312. doi:10.1111/jeb.12291
2013
Host nutrition alters the variance in parasite transmission potential.
Vale PF, Choisy M, Little TJ.
Biol Lett. 2013;9: 20121145. doi:10.1098/rsbl.2012.1145
Killing them softly: managing pathogen polymorphism and virulence in spatially variable environments.
Vale PF.
Trends Parasitol. 2013;29: 417–422. doi:10.1016/j.pt.2013.07.002
Elevated maternal temperature enhances offspring disease resistance in Daphnia magna.
Garbutt JS, Scholefield JA, Vale PF, Little TJ.
Functional Ecology. 2013; n/a-n/a. doi:10.1111/1365-2435.12197
2012
The distribution of mutational fitness effects of phage φX174 on different hosts.
Vale PF, Choisy M, Froissart R, Sanjuán R, Gandon S.
Evolution. 2012;66: 3495–3507. doi:10.1111/j.1558-5646.2012.01691.x
Fecundity compensation and tolerance to a sterilizing pathogen in Daphnia.
Vale PF, Little TJ.
J Evol Biol. 2012;25: 1888–1896. doi:10.1111/j.1420-9101.2012.02579.x
Genetic influence on disease spread following arrival of infected carriers.
Fellous S, Duncan AB, Quillery E, Vale PF, Kaltz O.
Ecol Lett. 2012;15: 186–192. doi:10.1111/j.1461-0248.2011.01723.x
2011
Epidemiological, evolutionary, and coevolutionary implications of context-dependent parasitism.
Vale PF, Wilson AJ, Best A, Boots M, Little TJ.
Am Nat. 2011;177: 510–521. doi:10.1086/659002
2010
CRISPR-mediated phage resistance and the ghost of coevolution past.
Vale PF, Little TJ.
Proceedings of the Royal Society B: Biological Sciences. 2010;277: 2097–2103. doi:10.1098/rspb.2010.0055
Successfully resisting a pathogen is rarely costly in Daphnia magna.
Labbé P, Vale PF, Little TJ.
BMC Evol Biol. 2010;10: 355. doi:10.1186/1471-2148-10-355
2009
Measuring parasite fitness under genetic and thermal variation.
Vale P, Little T.
Heredity. 2009;103: 102–109. doi:10.1038/hdy.2009.54
Infection outcomes under genetic and environmental variation in a host-parasite system: Implications for maintenance of polymorphism and the evolution of virulence.
Vale PF.
PhD, University of Edinburgh. 2009. Available: https://www.era.lib.ed.ac.uk/handle/1842/3189
2008 and earlier
The role of the environment in the evolutionary ecology of host parasite interactions.
Vale PF, Salvaudon L, Kaltz O, Fellous S.
Infect Genet Evol. 2008;8: 302–305. doi:10.1016/j.meegid.2008.01.011
Temperature-dependent costs of parasitism and maintenance of polymorphism under genotype-by-environment interactions.
Vale PF, Stjernman M, Little TJ.
J Evol Biol. 2008;21: 1418–1427. doi:10.1111/j.1420-9101.2008.01555.x
Parasite transgenerational effects on infection.
Little T, Birch * Jane, Vale P, Tseng M.
Evol Ecol Res. 2007;9: 459–469.
Comportamento social em bactérias. O papel dos cheaters na evolução da resistência a antibióticos.
Vale PF.
Universidade de Évora; 2004. Available: https://catalogo.bib.uevora.pt/cgi-bin/koha/opac-detail.pl?biblionumber=150442
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